Renya Karasuma/Relationships

Gin
Renya Karasuma's Subordinate. Gin often acts as the intermediary between the Boss and other Black Organization Members. He follows the Boss' orders closely and never acts against the syndicate's greater interests. In return, the Boss entrusts Gin to direct critical missions and key assassinations.

The Boss issues orders to Gin directly by text message for him to disseminate to his subordinates. The two are also implied to contact each other fairly often about instructions and suspicions. Although Gin follows all orders from the Boss, he acts on his own initiative on more than one occasion, such as deciding to poison Shinichi Kudo with APTX 4869 or to kill Vermouth if she does anything suspicious even if she is Boss' Favorite.

Pisco
Renya Karasuma's Former Subordinate. Pisco was a wealthy Car Company CEO who financed the Black Organization and served the Boss for many years.

During the Hotel Party Murder Case, Gin relayed the Boss' orders to Pisco which is to assassinate the Politician Shigehiko Nomiguchi and told him to use APTX 4869 when necessary. Although Pisco successfully assassinated the politician, he was accidentally caught on camera in the act of committing the murder. Fearing that Pisco may expose the existence and goals of the Black Organization to the public, the Boss ordered Gin to silence Pisco and his family, which the latter does even though Pisco knew where Sherry is.

Rum
Renya Karasuma's Subordinate. Rum is known as the Boss' Close Adviser and the Second-In-Command of the Black Organization. As the Boss' Close Adviser, the Boss trusts him the most enough to make Rum the highest ranking Executive Agent. In return, Rum aids the Boss in directing the activities and advancing the interests of the Black Organization.

Vermouth
Renya Karasuma's Subordinate. Vermouth is known as the Boss' Favorite, although the reason for the favoritism is unknown. As the Boss' Favorite, the Boss grants her limited independence and protects Vermouth from other Black Organization Members who hates, mistrusts and wishes to kill her.

Bourbon reveals that there is some sort of connection between the Boss and Vermouth, implying that the relationship of the two goes further than merely being his favorite member. Utilizing this as leverage to enlist Vermouth's assistance and protection, Bourbon also points out that the other Black Organization Members would be quite surprised if they knew the true nature of the relationship.

Rikumichi Kusuda
Renya Karasuma's Former Subordinate. For assurance, the Boss sends Rikumichi Kusuda to Haido Central Hospital to act as a patient while searching for Kir, who was held captive by the FBI. Kusuda continues to report to the Boss by phone everyday until he was cornered to death by Shuichi Akai.

Atsushi Miyano
Renya Karasuma's Former Subordinate. Several years ago prior to the current timeline, the Karasuma Group offered to sponsor the Miyano's Research and hire Atsushi and Elena as researchers of the company. At first, Atsushi was reluctant to accept their offer after hearing strange and shady rumors surrounding the conglomerate. However, Atsushi had a change of mind and considered their offer after Elena announced that she was pregnant with Shiho Miyano.

Elena Miyano
Renya Karasuma's Former Subordinate. Elena, despite being warned by Mary Sera about the shady rumors surrounding the conglomerate, joined Atsushi to work for the Karasuma Group after they were offered to be researchers of the company.

Kyosuke Senma
Renya Karasuma's Acquaintance. Kyosuke Senma was an archeologist who Renya Karsuma invited to his manor 40 years ago. He wanted Kyosuke to find the treasure before he died of old age. He also made copies of the riddle on a cheap mimeograph print on straw paper to hand out and left one stuck between the piano keys. Kyosuke claimed that it was a very well-paid job.

Kyosuke' Wife and then 23-year-old daughter Furuyo Senma received large sums of money, along with a letter from him, almost every day. But after six months, the money and letters suddenly stopped coming. Kyosuke, who had never given his current address, vanished forever. After investigating the events behind his father's disappearance, Furuyo only found out the truth when she held his last letter against a light, which she had kept as a memento.

Kyosuke had written a secret note by poking tiny holes in the paper left for her with a needle. He recorded the riddle of the treasure and wrote that many other scholars had been invited to the manor. He also wrote that Renya Karasuma had begun to kill those scholars, one by one, as a motivation for the others to solve the riddle faster. He also stated that even if he found the treasure, he too will be killed. Despite the revelation, Furuyo decided to investigate further by herself and chose not to tell the police about the occurrence since the event occurred 20 years ago, when Renya Karasuma had allegedly passed on.

Presumably a victim of Renya Karasuma's treasure hunting fanaticism, Kyosuke did solve the riddle and left a clue about it in a note letter hidden in a piano. The clue, which is written in blood, was revealed using luminol, concealing the key to the riddle which is "Trump Card" referring to the respective playing card ranks. After Furuyo discovered the key to the riddle, she was taken into custody after murdering a colleague whom she conspired with to arrange a detective gathering and make them find the treasure hidden in Sunset Manor.

Shuichi Akai
Renya Karasuma's Former Subordinate. Capturing a high ranking member of the Black Organization who could lead the FBI to the Boss was the goal of Akai's spy mission. After three years of infiltration, he gave the undercover FBI Agent the Black Organization Codename "Rye" and ordered him to work under the Executive Agent Gin. The FBI, in an attempt to capture Gin, laid a trap at a warehouse where the meeting between them was supposed to take place. However, their plan fell apart when Akai's true allegiance was uncovered due to a mistake made by FBI Agent Andre Camel.

Considering that the FBI Agent successfully infiltrated the Black Organization for five consecutive years, he came to regard Akai as the syndicate's "Silver Bullet", the threat whom the Boss fears the most.

Hidemi Hondou
Renya Karasuma's Subordinate. The Boss promoted Kir after reportedly uncovering a spy and confronting him. According to Kir's narrative, CIA Agent Ethan Hondou who was infiltrating the Black Organization, overpowered and tortured her for information. However, despite the inhumane treatment, Rena Mizunashi remained silent. Rena then bit Ethan's wrist to force him to drop his gun, and used it to kill him. The bite marks and Ethan's recording device coincided with her story. In recognition of her loyalty and sheer savageness, the Boss promoted Rena Mizunashi and gave her the Black Organization Codename "Kir".

In truth, the Boss was fooled. Ethan Hondou was Kir's Father and they are both CIA Agents infiltrating the Black Organization. When Rena Mizunashi met with his father in a location where she was not supposed to be, she realized that she made a mistake and was about to be uncovered as a spy. Ethan, who had appropriately prepared ahead of time in case such a scenario happened, told his daughter to make it seem that she discovered a spy and tried to confront him. Ethan then committed suicide after maiming himself and his daughter to fabricate the story Ethan had just explained.

At some point later, the Boss orders Kir to assassinate the Politician Yasuteru Domon, fearing that the politician may impose a greater threat to the Black Organization. The assassinate plot was successfully averted by the combined efforts of Conan Edogawa and the FBI. However, the FBI's plan to arrest Vermouth backfired and injured Kir instead. Kir was then captured by the FBI and was hospitalized in Haido Central Hospital for weeks.

After the Black Organization easily retrieved Kir from the FBI, Gin became suspicious of how ineffective the FBI's plan was and the fact that Akai did not made a strong move. Gin thought that Akai is planning something and relays his doubt to the Boss, who also agrees. The Boss and Gin planned a test of Kir's loyalty.

Meanwhile, FBI Agent Andre Camel becomes a suspect in a coincidental murder case and the Black Organization hears about the occurrence. Taking advantage of the FBI's distraction, Gin calls out Kir and tells her the Boss' Test of Loyalty. In order to regain the Boss' trust, she must call out Akai to meet with her and kill him. Kir then meets with Akai at Raiha Pass and eventually murders him. The Boss, however, was fooled again into thinking that Akai was killed. Conan, who had anticipated that such event may happen in the future, concocted a plan with Akai to conspire with Kir and fake his death.

Rei Furuya
Renya Karasuma's Subordinate. The Boss dispatches Bourbon to search for the escaped scientist Shiho Miyano. However, Bourbon prioritizes his second secret mission authorized by the Boss which is to verify Akai's Death. In truth, Rei had been persevering to turn Akai to the Black Organization to earn a higher rank and approach the Boss more closely.

Yasuteru Domon
Renya Karasuma's Former Target. After anticipating Domon's potential to become the Japan's next Prime Minister, the Boss ordered his assassination before Domon's strong sense of justice could even pose a greater threat to the Black Organization. The Boss then calls off the assassination plot after Domon puts a halt to his candidacy.

Shiho Miyano
Renya Karasuma's Former Subordinate. The Boss orders the execution of Shiho Miyano after she boycotted the development of APTX 4869 and rebelled against the Black Organization. Before she could even be executed, Shiho manages to escape and the Boss orders the Black Organization to hunt and execute the escaped scientist. Conan figures out the Boss' full number but Ai Haibara warns him not to call it, comparing the Boss' Cell Phone Number to a Pandora's Box.

Shigehiko Nomiguchi
Renya Karasuma's Former Target. After Nomiguchi was found out accepting bribes to keep sensitive information, the Boss ordered his assassination before the police could even carry out their arrest.